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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EFHD2
All Species:
19.7
Human Site:
S146
Identified Species:
36.11
UniProt:
Q96C19
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96C19
NP_077305.2
240
26697
S146
E
V
D
E
D
F
D
S
K
L
S
F
R
E
F
Chimpanzee
Pan troglodytes
XP_001156210
410
44344
S316
E
V
D
E
D
F
D
S
K
L
S
F
R
E
F
Rhesus Macaque
Macaca mulatta
Q5TM25
147
16701
K76
S
L
K
R
M
L
E
K
L
G
V
P
K
T
H
Dog
Lupus familis
XP_848956
248
27200
S154
E
V
D
E
D
F
D
S
K
L
S
F
R
E
F
Cat
Felis silvestris
Mouse
Mus musculus
Q9D8Y0
240
26773
S146
E
V
D
E
D
F
D
S
K
L
S
F
R
E
F
Rat
Rattus norvegicus
Q4FZY0
239
26741
S145
E
V
D
E
D
F
D
S
K
L
S
F
R
E
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518105
170
19250
D98
A
A
G
E
L
Q
E
D
S
G
L
H
V
L
A
Chicken
Gallus gallus
P09860
161
18412
K90
R
C
M
K
D
D
S
K
G
K
T
E
E
E
L
Frog
Xenopus laevis
NP_001089944
202
23367
G124
I
F
R
K
A
A
A
G
E
L
E
E
D
S
G
Zebra Danio
Brachydanio rerio
NP_001038676
233
26492
G139
E
V
D
E
D
L
D
G
K
L
S
F
R
E
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VJ26
217
25068
G123
E
V
D
E
D
N
D
G
K
I
S
F
R
E
F
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001176294
193
22506
S120
A
G
E
L
M
E
D
S
G
L
N
L
L
A
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LQN4
166
18399
Q95
T
T
P
Y
T
E
E
Q
L
L
R
L
F
R
I
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
58
25.8
62
N.A.
94.1
93.3
N.A.
60
20
70.4
75
N.A.
45.8
N.A.
N.A.
53.3
Protein Similarity:
100
58.2
37.9
68.9
N.A.
97
96.6
N.A.
64.1
38.7
76.6
83.7
N.A.
60.8
N.A.
N.A.
63.7
P-Site Identity:
100
100
0
100
N.A.
100
100
N.A.
6.6
13.3
6.6
86.6
N.A.
80
N.A.
N.A.
20
P-Site Similarity:
100
100
20
100
N.A.
100
100
N.A.
13.3
26.6
20
86.6
N.A.
86.6
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
22
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
36.2
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
16
8
0
0
8
8
8
0
0
0
0
0
0
8
8
% A
% Cys:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
54
0
62
8
62
8
0
0
0
0
8
0
0
% D
% Glu:
54
0
8
62
0
16
24
0
8
0
8
16
8
62
0
% E
% Phe:
0
8
0
0
0
39
0
0
0
0
0
54
8
0
54
% F
% Gly:
0
8
8
0
0
0
0
24
16
16
0
0
0
0
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
8
% H
% Ile:
8
0
0
0
0
0
0
0
0
8
0
0
0
0
8
% I
% Lys:
0
0
8
16
0
0
0
16
54
8
0
0
8
0
0
% K
% Leu:
0
8
0
8
8
16
0
0
16
70
8
16
8
8
8
% L
% Met:
0
0
8
0
16
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
8
0
0
0
0
8
0
0
0
0
% N
% Pro:
0
0
8
0
0
0
0
0
0
0
0
8
0
0
0
% P
% Gln:
0
0
0
0
0
8
0
8
0
0
0
0
0
0
8
% Q
% Arg:
8
0
8
8
0
0
0
0
0
0
8
0
54
8
0
% R
% Ser:
8
0
0
0
0
0
8
47
8
0
54
0
0
8
0
% S
% Thr:
8
8
0
0
8
0
0
0
0
0
8
0
0
8
0
% T
% Val:
0
54
0
0
0
0
0
0
0
0
8
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _